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HR 2541119th CongressIn Committee

Nuclear Medicine Clarification Act of 2025

Introduced: Apr 1, 2025
Standard Summary
Comprehensive overview in 1-2 paragraphs

The Nuclear Medicine Clarification Act of 2025 would require the Nuclear Regulatory Commission (NRC) to revise its medical-event reporting rules to specifically address unintended radiation exposure from extravasation during nuclear medicine procedures. Extravasation is when radiopharmaceuticals leak into surrounding tissue instead of remaining in the vein, potentially delivering higher, localized doses to tissue or skin. The bill adds new reporting thresholds: if a dose caused by extravasation exceeds 0.5 Sv (50 rem) to the most exposed 5 cubic centimeters of tissue during residence time, or 0.5 Sv (50 rem) to the most exposed 10 square centimeters of skin during residence time, it would be considered a medical event requiring reporting. The NRC must complete the regulatory revision within 120 days of enactment, and the revised rules would take effect 18 months after enactment. The aim is to strengthen patient safety and transparency around significant extravasation events in nuclear medicine.

Key Points

  • 1Adds new criteria to medical-event reporting for nuclear medicine, specifically addressing extravasation.
  • 2Thresholds: 0.5 Sv (50 rem) to the 5 cm³ of tissue with the highest dose, or 0.5 Sv (50 rem) to the contiguous 10 cm² of skin with the highest dose, during residence time.
  • 3NRC must revise 10 CFR 35.3045(a)(1) to include these criteria within 120 days after enactment.
  • 4The new reporting requirements become effective 18 months after enactment.
  • 5The bill is titled the Nuclear Medicine Clarification Act of 2025 and aims to enhance patient safety and accountability in nuclear medicine procedures.

Impact Areas

Primary group/area affected: Nuclear medicine patients and facilities (hospitals, clinics) that perform radiopharmaceutical injections; medical physicists and radiologists responsible for dosimetry and safety.Secondary group/area affected: NRC and hospital regulatory/compliance programs; radiation safety officers; medical event reporting workflows and investigations.Additional impacts: Potential changes in training, dosimetry practices, and quality assurance to detect and quantify extravasation; possible implications for liability and patient communications when reportable events occur; need for imaging and dosimetry protocols to determine residence time and dose to tissue and skin.
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