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S 1407119th CongressIn Committee

ABC Safe Drug Act

Introduced: Apr 10, 2025
Standard Summary
Comprehensive overview in 1-2 paragraphs

The ABC Safe Drug Act would, if enacted, section off U.S. federal health program drug purchases from drugs whose active ingredients are manufactured in China and push toward domestic or FDA-approved non-China sources. Beginning in 2028, federal health programs would be limited to drugs with at least 60% of their active pharmaceutical ingredients (APIs) manufactured in FDA-compliant countries outside the People’s Republic of China; by 2030, purchases would be limited to drugs with 100% of APIs manufactured in such non-China countries. The act allows waivers for agencies unable to meet the standard but forbids waivers for drugs bought on or after January 1, 2031. It also adds a labeling requirement to disclose the country of origin for each API. Separately, the bill offer a temporary 100% expensing bonus depreciation for new qualifying pharmaceutical and medical device manufacturing property placed in service from 2025 through 2030, aiming to boost domestic U.S. manufacturing capacity, with a sunset on 2030.

Key Points

  • 1Phased restriction on federal health program drug purchases: starting January 1, 2028, agencies may purchase only drugs with 60% or more of APIs manufactured in FDA-approved countries other than China; by January 1, 2030, 100% of APIs must be manufactured in such countries.
  • 2Countries described: non-China countries that meet Food and Drug Administration health and safety standards; the restriction targets drugs manufactured outside PRC, subject to waivers if agencies cannot meet the requirement (but no waivers for purchases after 1/1/2031).
  • 3Labeling requirement: adds a new requirement that drug labeling specify the country of origin for each active ingredient.
  • 4Tax incentive for domestic manufacturing: provides temporary 100% expensing (bonus depreciation) under the tax code for qualified pharmaceutical and medical device manufacturing property placed in service between 2025 and 12/31/2030, to encourage U.S. manufacturing capacity.
  • 5Termination and sunset: the 100% expensing incentive applies only to property placed in service through 12/31/2030; after that, the expensing would end, and the procurement waivers model would also phase toward full non-China API sourcing by 2031.

Impact Areas

Primary group/area affected: Federal health programs and beneficiaries (e.g., Department of Health and Human Services, Department of Veterans Affairs, Department of Defense) and the drug supply chain that serves these programs; U.S. drug manufacturers and contract manufacturers that produce APIs or finished drugs; FDA-regulated drug labeling practices.Secondary group/area affected: Non-China API suppliers and international drug manufacturers; hospitalization providers and clinicians who rely on KOLs and drug availability; taxpayers and federal budget due to potential shifts in procurement costs and the cost impact of new domestic manufacturing investments.Additional impacts: Potential shift in global pharmaceutical supply chains away from China toward FDA-reviewed non-China suppliers; increased compliance and labeling costs for drugs; possible price effects or supply constraints for certain medicines during the transition; incentives to expand domestic manufacturing infrastructure and employment in the pharmaceutical and medical device sectors.
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